Blood test could predict who is most at risk from common inherited heart condition

Scientists are developing a simple blood test to predict who is most at risk from the world’s most common inherited heart condition.Millions of people worldwide have hypertrophic cardiomyopathy (HCM), a disease of the heart muscle where the wall of the heart becomes thickened. It is caused by a change in one or more genes and mostly passed on through families.Some feel fine most of the time and have few or no symptoms. But others can suffer complications, such as heart failure and abnormal heart rhythms, which can lead to a cardiac arrest

Key figures in creation of Milton Keynes criticise England’s new towns plan

Senior planners involved in building the country’s postwar new towns have raised concerns about the government’s new towns programme, criticising a lack of ambition and insufficient commitment to social housing.Lee Shostak, former director of planning at Milton Keynes Development Corporation (MKDC) in the 1970s and later chair of the Town and Country Planning Association (TCPA), said the current plan for the new towns may not help people who need homes the most.He said that while Milton Keynes was designed specifically to ease the housing burden in London with a large stock of council housing, there was a real risk these new towns would do little to alleviate council house waiting lists in big cities.“There’s talk about 40% of the homes as affordable housing, most of which will not be social housing and there’s no indication whatsoever those homes will be available for people moving from London or other urban areas,” said Shostak.“So the very basic, simple premise that kickstarted the original new towns programme isn’t being followed through today

Midwife leading Nottingham maternity inquiry charging NHS up to £26,000 a month

The midwife leading the biggest inquiry into maternity failures in the history of the NHS is charging NHS England up to £26,000 a month for her advice through her company, the Guardian can reveal.Donna Ockenden, who has been chairing a review into maternity failings at Nottingham university hospitals NHS trust since 2022, is paid an £850 daily rate for every 7.5 hours she works.When asked about her monthly invoices of up to £26,000 for her advice, she said: “I am working long hours.”The monthly charges for “provision of independent advice” in connection with the review do not include the wider costs of the inquiry that are charged to NHS England (NHSE)

‘For the first time, she could tell people who she was’: Ireland’s gender recognition decade

Soon after Ireland passed its Gender Recognition Act in 2015, Kevin Humphreys, a Labour politician, visited a residential home for senior citizens – where an older woman thanked him for the new law.It was Humphreys who, as the minister of state for social protection 10 years ago, guided through the legislation that has meant transgender people in Ireland can apply to have their lived gender legally recognised by the state through a simple self-certification process.“She was around 80,” Humphreys recalls, “and for the first time she was able to tell her friends and family she was transgender. She told me the relief she felt to be accepted by her own community, and by the state, in the last few years of her life.”“We were very fortunate in Ireland that we were able to do the legislation in an era of openness and progressive discussion,” he says

Resident doctors say they will resume talks to avoid further strikes with ‘can-do spirit’

Resident doctors have said they will approach talks with Wes Streeting with a “can-do spirit” to avoid further strikes in the new year, as their five-day action ended on Monday morning.The British Medical Association called on the health secretary to come to the table with the same “constructive” attitude, saying the tone of 11th-hour talks before their stoppage had been encouraging but too late to avoid the strike in England.Streeting also signalled his determination to get back to the talks, saying he did “not want to see a single day of industrial action in the NHS in 2026”, and that he would “be doing everything I can to make this a reality”.“My door remains open, as it always has done, and I’m determined to resume discussions with the BMA in the new year to put an end to these damaging cycles of disruption,” he said.Streeting and Keir Starmer have taken a tough line towards the strike, with the prime minister saying it was “beyond belief” that it should go ahead when the flu-hit NHS was facing its worst crisis since Covid

Christmas burnout: why stressed parents find it ‘harder to be emotionally honest with children’

Advent calendars, check. Tree and decorations, check. Teachers’ presents, nativity costumes and a whole new ticketing system for the PTA’s Santa’s grotto, check. But the Christmas cards remain unwritten, the to-do list keeps growing, and that Labubu doll your child desperately wants appears to have vanished from the face of the earth.If you’re feeling frayed in the final days before Christmas, you’re not alone