Microdosing: how ‘off-label’ use of weight loss jabs is spreading from US to UK

A slim woman standing in a kitchen injects herself in the abdomen. Another jogs. A third kneels on a yoga mat drinking water. The shots are intercut with a doctor telling the viewer: “Usually it’s for people who don’t actually have that much to lose – it’s a bit of a gentler way to get to your target weight.”The promotional video is from a private clinic in Leicester offering “microdosing”, the latest trend in the weight loss jab revolution

‘The Co-op won’t defeat me’: Brighton shop owners fight against eviction

For Louise Oliver, it is the work of Charles Dickens that best describes her current predicament. “It’s a tale of a woman who has her lovely old shop taken over by a nasty piece of work,” she said, evoking Dickens’s The Old Curiosity Shop.In this instance, the identity of this “nasty piece of work” may come as a surprise. In 1844, three years after Dickens published the tragic tale of Little Nell, the world’s first successful cooperative shop opened in Rochdale. It put power into the hands of the community, who were sick of being fleeced by the powers above

Louis Vuitton says UK customer data stolen in cyber-attack

Louis Vuitton has said the data of some UK customers has been stolen, as it became the latest retailer targeted by cyber hackers.The retailer, the leading brand of the French luxury group LVMH, said an unauthorised third party had accessed its UK operation’s systems and obtained information such as names, contact details and purchase history.The brand, which last week said its Korean operation had suffered a similar cyber-attack, told customers that no financial data such as bank details had been compromised.“While we have no evidence that your data has been misused to date, phishing attempts, fraud attempts, or unauthorised use of your information may occur,” the email said.The company said it had notified the relevant authorities, including the Information Commissioner’s Office

The CEO who never was: how Linda Yaccarino was set up to fail at Elon Musk’s X

In May 2023, when Linda Yaccarino, an NBC advertising executive, joined what was then still known as Twitter, she was given a tall order: repair the company’s relationship with advertisers after a chaotic year of being owned by Elon Musk. But just weeks after she became CEO, Musk posted an antisemitic tweet that drove away major brands such as Disney, Paramount, NBCUniversal, Comcast, Lionsgate and Warner Bros Discovery to pause their advertising on the platform. Musk delivered an apology for the tweet later at a conference – which he called the worst post he’s ever done – but it came with a message to advertisers, specifically the Disney CEO Bob Iger: “Go fuck yourselves.” Yaccarino was in the audience of the conference.“I don’t want them to advertise,” he said

Pressure mounts on Konstas and Khawaja as Australia collapse against West Indies

It was a strange way to start. Out of Australia’s last 146 Test matches before taking the field at Sabina Park in Jamaica on Saturday, off spinner Nathan Lyon had missed seven. Four of those were in 2012 and 2013, left out for other configurations of bowlers. Three were after he blew out his calf during the 2023 Ashes. And that was that

Jannik Sinner seeks instant revenge in latest instalment of rivalry with Carlos Alcaraz

Great sport is all about rivalry. In the 70s and 80s, tennis had Martina Navratilova and Chris Evert, who played against each other a whopping 80 times, 60 of them in finals. In the last half-century, men’s tennis has been lucky to have Björn Borg and John McEnroe, Jimmy Connors and McEnroe, Boris Becker and Stefan Edberg, Pete Sampras and Andre Agassi and any combination you choose of Novak Djokovic, Rafael Nadal and Roger Federer. Now we have Carlos Alcaraz and Jannik Sinner.Alcaraz and Sinner have played each other 12 times, with Alcaraz leading 8-4 after winning their incredible match in the French Open final last month, when the Spaniard saved three match points before triumphing in an epic five-setter